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Genome Guardian

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About Genome Guardian

Genome Guardian is a shooter set in a microscopic world filled with bioluminescent life and microbes. You research permanent upgrades and combine DNA nucleotides to create hybrid bioweapons. The game has six modes, each with multiple depths.

Build hybrid weapons

Adenine gives weapons rapid fire, Cytosine adds precision, Guanine creates spread, and Thymine brings explosive power. Combining them can produce weapons such as the Blast Shotgun, which mixes bombs and shotgun spread; the Bazooka, made by combining bombs; and the Flak Cannon, formed from a Blast Shotgun and a Shotgun.

Change each run

You can choose from 49 turrets with distinct strengths and functions, 96 perks to mix and match, and 75 weapon and turret mods. Mods can turn shots into sticky laser mines or bouncing fireballs. There are also 64 mutations that alter the challenges you face on each run. Runs last 20 minutes and can continue in Endless Mode.

Additional content

The game includes 75 electronic music tracks that adapt to the current mood and intensity, along with cosmetics such as spider legs and tank treads. Accessibility settings cover colourblindness, motion sickness and arachnophobia.

Frequently asked questions

Buy Genome Guardian 88% cheaper than on Steam.

Genome Guardian is available for 88% less in shops such as Kinguin, Eneba, or Driffle.

Steam lets publishers create keys to sell in other shops. Once you activate a key, the game is yours to keep, just like a store purchase.

Disclaimer: CD keys have an inherent 1–2% average failure rate. Check the shop terms for buyer protection info. Steam offers no buyer protection for keys bought in other shops and doesn't refund them.

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