Genome Guardian 2

Genome Guardian 2 returns to a microscopic world filled with bioluminescent life and dangerous microbes. You build a biomechanical machine from different parts, which determine how it shoots, behaves and moves, then take it into runs against varied microbes and modes. Research permanent upgrades to improve your chances of survival.

Build your machine

Combine parts to create machines ranging from stationary turrets to psychic water sprinkler motorbikes and dual-wielding fidget spinner Gundams. You can recreate turrets from the first game or combine them into a single machine. Save and load up to 24 loadouts, and customize their paint and patterns.

Discover bioweapons

Pair DNA nucleotides to create 70 hybrid bioweapons: A provides rapid fire, C precision, G spread and T explosive effects. Combining a Shotgun with a Bomb makes a Blast Shotgun, while an SMG and Pistol produce the accurate, fast-firing Scout Rifle. Combining those two weapons creates another, crazier result.

Runs and modes

Runs last 20 minutes and can be saved and resumed at any time. Genome Guardian 2 also includes an improved Endless Mode. During runs, you can complete side objectives for extra cash, mine mineral deposits for resources and activate powerful Gadgets. Discovered weapons can be tested in the Database.

Music and options

The game includes 100 bassy electronic tunes, with an in-game Jukebox available at any time, as well as a Streamer Mode. Auto-aim and auto-fire can be toggled, and keyboard and gamepad controls can be fully rebound. Accessibility options address colourblindness, motion sickness and arachnophobia. The game also includes 100 Steam achievements and cloud saves, and is described as playing well on Steam Deck.