STEM Defense

STEM Defense is an educational tower defense game set within the human body. You arrange defenses on a dynamic hexagonal grid to protect against microscopic invaders and learn about the immune system.

Shape the battlefield

You can extend the pathways pathogens travel along, shaping each level and influencing how effectively your defenses can attack them. Tower placement is important, and elevating towers gives them damage bonuses.

Adapt your defenses

Epigenetic modifications provide temporary boosts, while genetic mutations make permanent enhancements. You gain experience to unlock advanced defensive capabilities and permanent genetic upgrades.

Face changing threats

Pathogens have varied abilities: some regenerate, accelerate or spawn additional threats. Genetic enhancements and adaptive enemy tactics create new challenges and decisions across playthroughs.