S.E.M.I.: Side Effects May Include...

S.E.M.I.: Side Effects May Include... is an online co-op game for up to four players. You and your friends play as patients trying to escape a special clinic, fighting staff and other patients while dealing with obstacles, puzzles, deadly traps and rooms where one wrong move can knock out the whole group.

Escape the clinic

Locations are randomly generated from rooms with changing gravity, traps, moving walls and other hazards. You use close combat, physics, abilities and voice chat to coordinate, help friends through rooms and traps, and sabotage one another as you face opponents. After a successful escape, you receive a medical report describing the patient’s conduct and diagnosis.

Pills and side effects

Pills grant abilities, but their effects can make them difficult to control. The four listed side effects are:

• Bipolar force: become an invulnerable monster, then a helpless rag.
• Laser astigmatism: use two sights and one laser, with uncertain aim.
• Stendhal syndrome: become hysterical and destroy everything around you when looking at a painting.
• Alice's syndrome: become tiny or gigantic and adjust to the change.

Madness can take hold, making you run, jump and fight while your abilities become uncontrollable. Taking pills lets you try to regain control. You can also unlock new costumes and decorations to style each escape.