Immunica

Immunica puts you in control of the immune system as pathogens flood in and your health drops. Move and position your cursor to fight invading waves: hovering over enemies deals damage, while your weapons attack automatically. The game combines active survival with idle progression, and your goal is to collect enough Vaccine Data to complete the cure.

Fight pathogen waves

Your cursor is your primary weapon, and four weapon systems support it:

• Burst: an area-of-effect pulse centered on your cursor.
• Missiles: homing projectiles that seek targets.
• Beam: a high-damage laser for focused attacks.
• Drones: orbiting allies that intercept incoming threats.

Chaining kills fills your Fever meter. When it is full, Fever unleashes up to +500% damage across five escalating tiers; more kills make you stronger. Each run randomly selects 1–3 breach modifiers from 30 possibilities. Buffs increase your power, nerfs raise the difficulty while offering bonus protein rewards, and weird modifiers can change how the game plays.

Face evolving pathogens

The game features 40+ pathogen species, representing eight pathogen types across multiple tiers. They range from tiny Prions to massive Helminths, each with distinct behavior patterns. Every pathogen has three evolution levels: Normal, Mutant and Alpha. Higher tiers bring deadlier enemies and greater rewards.

Research the cure

Between breaches, you manage a research laboratory. Collect pathogen samples in combat and assign them to scientists, including interns, technicians, researchers and senior scientists. Each has different processing speeds, efficiency rates and capabilities. Your team continues analyzing samples while you are away, with offline progress lasting up to eight hours.

Upgrade your defenses

More than 200 upgrades across multiple categories let you improve cursor damage, fire rate and critical chance, unlock and strengthen weapons, and increase core health and damage resistance. Spending protein makes you permanently stronger, and progression persists across runs. Hidden synergies offer further effects to discover through gameplay.