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Against the Gradient

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About Against the Gradient

Against the Gradient is a puzzle game about cellular transport. You place transporters in cell membranes to move molecules and ions into or out of cells, aiming to reach specific concentrations.

Cellular transport puzzles

More than 20 puzzles introduce the principles of cellular transport, from gentle introductions to challenging puzzles. You use channels, co-transporters and antiporters to work with facilitated diffusion and active transport. The mechanics are based on real biological principles, and you can speed up or slow down time to play at your own pace.

Transporters and level editor

The game includes 16 transporters, including real proteins found in the human body and imaginative nano-robots. A built-in level editor lets you create your own puzzles to challenge your friends.

Frequently asked questions

Steam lets publishers create keys to sell in other shops. Once you activate a key, the game is yours to keep, just like a store purchase.

Disclaimer: CD keys have an inherent 1–2% average failure rate. Check the shop terms for buyer protection info. Steam offers no buyer protection for keys bought in other shops and doesn't refund them.

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